"Amoxiclav": instructions for use


In the number of drugs for treatmentinfections caused by bacteria include amoxiclav. Instructions for use of this drug indicates its antibacterial pharmacological effect, and a fairly wide range.

Amoxiclav is a modern antibiotic. The active substances of this drug are amoxicillin (semisynthetic penicillin) and clavulanic acid (inhibitor of β-lactamases), supplementing each other in combination, since they are similar in their pharmacokinetic parameters. Amoxicillin is present in the preparation "Amoxiclav" (the instruction on the use gives information about it) as trihydrate, clavulanic acid - as potassium clavulanate. And if the first active substance in one tablet of the medicine is 500 mg, then the acid in it contains 125 mg. Among the auxiliaries of the preparation are talc, crospovidone, silicon colloidal dioxide, MCC, magnesium stearate, sodium croscarmellose. The package contains 15 tablets of "Amoxiclav" medication. They are oval, covered with a film of almost white color, biconvex.

Both ingredients of the drug"Amoxiclav" is perfectly distributed in tissues, such as the uterus, lungs, ovaries, the middle ear, as well as in pleural and peritoneal fluids. In addition, amoxicillin has the property of penetrating the liver, gall bladder, saliva, synovial fluid, the secret of the paranasal sinuses, the prostate gland, muscle tissue, bronchial secretion, palatine tonsils. With the help of clavulanic acid, in which weak antibacterial activity, stability of amoxicillin to the action of β-lactamases is provided. They are produced by microorganisms (aerobic gram-negative and gram-positive bacteria, anaerobes gram-positive and gram-negative, etc.).

The drug "Amoxiclav" instructions for useadvises to take in the treatment of infectious and inflammatory diseases that are caused by microorganisms that are most sensitive to the active substances of the drug. These are infections:

  • ENT organs and the respiratory system, its upper parts (such as the abscess of the pharynx, sinusitis chronic, pharyngitis, otitis media (chronic and acute), tonsillitis);
  • respiratory system of the lower parts (including bronchitis (acute and chronic) and pneumonia);
  • urinary system;
  • gynecological;
  • soft tissues, skin (including animal and human bites);
  • connective and bony tissues;
  • biliary tract;
  • odontogenic.

Since this medicine is available in the form oftablets, powders, drops, suspensions and as a solution for intravenous injection, then the dosage in them is different. So, the tablet "Amoxiclav 250" instructions for use advises adults to take one 3 times a day, and under 14 years of age, children should choose a suspension (1.5-2 tsp-all depends on the child's age) or drops that give a day 3 times 0.75-1.25 mg. If the doctor has prescribed an intravenous amoxiclav (instruction for 1000 mg use indicates), then slowly, every six to eight hours, the drug is injected slowly into 1.2 mg adults and children 12 years of age. If the child does not have 12, then from the calculation of 30 milligrams per kilogram of weight.

Pharmaceutical companies produce analoguesmeans "Amoxiclav," similar in composition and in action. These are the preparations "Klavocin", "Moxicraft", "Amoclan", "Kuram", "Augmentin", "Clavunate", "Amoclavine", etc.

Store such a drug as "Amoxiclav" should be out of reach of children's handles and that the air temperature does not exceed 25 degrees.

Are there any contraindications and side effects inmeans "Amoxiclav"? Instructions for use on this have information. Thus, it is not recommended to take this medication for those patients who have an increased susceptibility to antibiotics that are part of the groups of cephalosporins and penicillins, to components of amoxiclav, who have liver disorders, etc. In any case, carefully read the instructions before using the medication.

There are when taking amoxiclav and side effects from the gastrointestinal system (diarrhea, vomiting, nausea, loss of appetite).

Take care of your health!