The drug "Ornidazole": instructions for use
The drug "Ornidazole" is antiprotozoala drug belonging to the group of antibiotics, the active component (nitroimidazole-5) of which has antimicrobial activity. The action of the drug is based on the reduction at the biolevel of the nitro group by transport proteins of anaerobic and protozoan microorganisms. As a result of the reduction process, the nitro group of the drug interacts with the DNA of microorganisms, which eventually leads to inhibition of the synthesis of nucleic acid in microorganisms, thereby causing the death of bacteria. The drug does not affect aerobic bacteria.
The antibiotic is in the form of tablets and a solution for infusions.
Pharmaceutical preparation "Ornidazole": instructions for use and indications
The drug is used to treat trichomoniasis,giardiasis, an abscess of amoebic origin in the liver. The drug is prescribed in gynecological practice, with the intestinal form of amebiasis, with surgical interventions on the large intestine and amoebic dysentery.
Medication Ornidazole: instructions for use, side effects and contraindications
Antibiotic is prohibited for use whenindividual intolerance to the active component of the drug. It is inadmissible to use the drug during pregnancy (1 trimester), with breastfeeding, with hypersensitivity and with organic diseases of the nervous system.
The list of side effects of the drug "Ornidazole"Instructions for use include dizziness, drowsiness, headaches, nausea, convulsions, dyspeptic disorders. As a result of taking medication, there may be impaired coordination of movements, muscle rigidity, increased liver enzymes, tremor of the extremities. The negative consequences also include allergic reactions, a mixed form of neuropathy, a change in taste, a temporary loss of consciousness.
Pharmaceutical "Ornidazole": instructions for use, dosage and method
Intravenous administration of the drug is prescribed for severe infectious diseases or when there is no possibility of taking the tablets inside.
Standard single dose for children older thantwelve years and adults is half a gram. Introduce "Ornidazole" (antibiotic) at a rate of five milliliters per minute. Between procedures, an 8-hour interval is required. At the same time, the maximum dose should not be higher than 2 grams per day. The duration of the course of treatment is determined by the doctor for each patient individually.
Depending on the indications and nature of the infection, maintenance treatment with oral metronidazole is determined to continue therapy.
To treat trichomoniasis, adults shouldtake a half a gram of antibiotic 3 times a day for five days or one gram in combination with the introduction of vaginal tablets (0.5 g) overnight. For children, the amount of the drug is calculated based on 25 mg per kilogram of body weight.
Amoebic dysentery is treated for three days,appointing for a patient weighing more than 35 kg and a half grams of the drug per day, more than 60 kg take 2 g. Children more than 35 kg should take 40 mg per kg of body weight.
For elimination of a lambliasis use the scheme, as well as for an amoebic dysentery, only the course of therapy makes 1-2 days.
For the prevention of infectious complications,caused by anaerobic bacteria after surgery, the drug "Ornidazole-Vera" takes 0.5 grams before the beginning of surgery, and then the same amount of antibiotic is used every 12 hours for five days.
The infusion solution can be combined withoral antibiotics in the treatment of mixed infections. However, with intravenous drip, the drug should not be combined with other pharmaceutical preparations.